Tag Archives: heart attack

Coronary Angioplasty


Coronary angioplasty is a non-surgical procedure used to widen coronary arteries with cholesterol plaques. It can also be performed as an emergency treatment for heart attack (myocardial infarction). 

The first part of the procedure is to localize the site of blockage (Fig. 1). This part is called cardiac catheterization and can be performed without subsequent angioplasty, i.e. just for diagnostic purposes.

Below is a narrated animation about myocardial infarction, cardiac catheterization and coronary angioplasty. Click here to license this video and/or other cardiovascular related videos on Alila Medical Media website.

A catheter (guiding catheter) is inserted through the femoral artery at the groin, or less commonly, through the radial artery in the arm (Fig. 1 and 2) and threaded all the way to the aorta. The tip of the catheter is placed at the beginning of the coronary artery to be investigated (it does not go inside the artery). A radio-opaque dye is injected through the catheter into the coronary artery. This enables real-time visualization of the artery using X-ray imaging. A narrowed part of an artery would appear as a bottle neck on an x-ray image (Fig.1).

Click here to see an animation of cardiac catheterization on Alila Medical Media website where the video is also available for licensing.

Cardiac catheterization
Fig. 1: Cardiac catheterization procedure for diagnosis of blocked site. Click on image to see a larger version on Alila Medical Media website where the image is also available for licensing.

 

 

 

After the location of stenosis (narrowed artery) is identified, angioplasty can begin. A thin guidewire with radio-opaque tip is inserted inside the guiding catheter and threaded past it into the location of plaque. Reminder : the guiding catheter stops at the start of coronary artery, but the guidewire would go further into it and to the location of blockage. An angioplasty catheter (a catheter with deflated balloon) is then inserted in such a way that the guidewire now is inside of it. The balloon is pushed to the location of blockage where it would be inflated and thus crushing the plaque (see Fig. 2 and 3). At the end of procedure, the balloon is again deflated and removed together with all catheters and guidewire.

Click here to see an animation of balloon angioplasty on Alila Medical Media website where the video is also available for licensing.
Coronary angioplasty
Fig. 2: Coronary angioplasty procedure. Click on image to see a larger version on Alila Medical Media website where the image is also available for licensing.


Balloon angioplasty procedure
Fig. 3: Balloon angioplasty procedure. The guidewire is the thin line that goes past the plaque. The guiding catheter is (of course) NOT on this picture as it stays outside of the coronary artery. Click on image to see a larger version on Alila Medical Media website where the image is also available for licensing.

 

 

 

In some cases, a stent is inserted together with the balloon (Fig. 4), inflated and left on place of the plaque to keep the artery open permanently. The stent can be bare-metal (the original version) or drug-eluting (newer versions). Bare-metal stents simply provide a mechanical support.  Drug-eluting stents are coated with various drugs that are released over time and act to prevent tissue growth at the site and/or modulate inflammatory response. The benefit of using stents is still debatable.
Stent angioplasty procedure
Fig. 4: Stent angioplasty procedure. Click on image to see a larger version on Alila Medical Media website where the image is also available for licensing.

 

 

 

 

Click here to see an animation of stent angioplasty on Alila Medical Media website where the video is also available for licensing.

                                                                           > See all Circulatory topics

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Heart attack


Myocardial infarction, commonly referred to as heart attack, is the sudden death of part of the heart muscle (the myocardium) due to loss of blood flow (ischemia). This occurs when one of  the coronary arteries – the arteries that supply blood to the heart – is blocked.
Coronary arteries, labeled diagram.
Fig. 1: Coronary arteries supply blood to the heart. They branch out from the first part of the aorta. Click on image to see a larger version on Alila Medical Media website where the image is also available for licensing.

 

 

 

The blockage is commonly due to atherosclerosis – cholesterol plaques/fat deposits on the wall of blood vessels. As the plaque builds up, the vessel becomes narrow restricting blood flow. Under stress, the plaque may rupture. This triggers formation of blood clot on top of the plaque leading to complete blockage of blood flow.  When this happens in a coronary artery, the downstream patch of the myocardium dies from lack of oxygen (Fig. 2). Weaken heart muscle may disrupt electrical activity of the heart and cause fibrillation with subsequent cardiac arrest.
heart attack
Fig. 2: Anatomy of a heart attack due to atherosclerotic plaque. Click on image to see a larger version on Alila Medical Media website where the image is also available for licensing.

 

 

 

 

Click here to see an animation of heart attack  on Alila Medical Media website where the video is also available for licensing.

Signs and symptoms

The most common symptom is described as a heavy pressure and squeezing pain inside the chest which often radiates to the shoulder and left arm. Other symptoms include shortness of breath, sweating, weakness, nausea and vomiting.

In a number of cases, especially in elderly and people with diabetes, no chest pain or other symptoms are reported. These are called silent myocardial infarction. In such a case, myocardial infarction is diagnosed later with electrocardiograms (ECG), blood enzyme tests or an autopsy.

Risk factors and Causes

Heart attack is caused by build-up of atherosclerotic plaques. Risk factors include smoking, alcohol consumption, obesity, sedentary lifestyle, stress. Incidence increases with age, also, men are more at risk than women.

Onset of acute myocardial infarction is commonly associated with physical and/or psychological exertion. When the body is under physical or emotional stress, blood flow is increased. This leads to stretching of the wall of blood vessels and potentially rupture of plaques.

Below is a narrated animation about myocardial infarction, cardiac catheterization and coronary angioplasty. Click here to license this video and/or other cardiovascular related videos on Alila Medical Media website.


Treatments

Immediate treatments for suspected heart attack include blood thinners such as aspirin. Blood thinners are drugs that prevent further blood clotting. If this doesn’t help, another class of drugs called thrombolytic may be used. Thrombolytic drugs act to dissolve blood clots. This process is called thrombolysis.

Severe cases will require interventional therapy such as angioplasty where the blocked blood vessel is forced to open wider with a balloon and possibly a stent.

People with multiple sites of blockage may require heart bypass surgery. In this surgical procedure, a piece of healthy artery or vein taken from elsewhere in the body is used as a graft to “bypass” the blocked part of coronary artery.

                                                                            > See all Circulatory topics

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